Jerzy Szablowski, Ph.D.
My long-term research goal is to develop technologies for perturbing and monitoring neural circuits to study brain function and treat brain disorders. I hope to achieve these goals through a combination of unique engineering strategies aimed at overcoming transport limitations in the brain using focused ultrasound, and allowing specific and efficient interfacing with the brain cells through biomolecular engineering.
My research focuses on controlling living cells within the deep tissues through ultrasound-mediated delivery and biomolecular engineering. I am currently focusing on development of noninvasive neuromodulation technology - Acoustically Targeted Chemogenetics (ATAC). In the past I worked with DNA-binding small molecule therapeutics, light-activated receptors and chemogenetic systems.
B.Sc. MIT, Biological Engineering, 2009
Ph.D. Caltech, Bioengineering, 2015, (Dervan Lab)
Postdoctoral, Caltech, Chemical Eng., (Shapiro Lab), 2015-current
Image: High-throughput screening for MRI contrast agent for a neurotransmitter dopamine (Frances Arnold's research group, 2007), one of the wells contains a BM3h-B7 a high-affinity clone described in the final publication.
replace x with caltech
1200 E California Blvd
Pasadena, Los Angeles County 91106