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Jerzy Szablowski, Ph.D.

My long-term research goal is to develop technologies for perturbing and monitoring neural circuits to study brain function and treat brain disorders. I hope to achieve these goals through a combination of unique engineering strategies aimed at overcoming transport limitations in the brain using focused ultrasound, and allowing specific and efficient interfacing with the brain cells through biomolecular engineering.

I am starting a new lab at Rice University in January 2020. For the future projects and open positions see the lab's website and my bioengineering faculty profile.

Rice_Engineering_Department of Bioengine


My research focuses on controlling living cells within the deep tissues through ultrasound-mediated delivery and biomolecular engineering. I am currently focusing on development of noninvasive neuromodulation technology - Acoustically Targeted Chemogenetics (ATAC). In the past I worked with DNA-binding small molecule therapeutics, light-activated receptors and chemogenetic systems. 

B.Sc. MIT, Biological Engineering, 2009

Ph.D. Caltech, Bioengineering, 2015, (Dervan Lab)

Postdoctoral, Caltech, Chemical Eng., (Shapiro Lab), 2015-current

Image: High-throughput screening for MRI contrast agent for a neurotransmitter dopamine (Frances Arnold's research group, 2007), one of the wells contains a BM3h-B7 a high-affinity clone described in the final publication.


Noninvasive control of brain circuits with Acoustically Targeted Chemogenetics


Noninvasive gene delivery to the brain


Programmable therapeutics for oncology


Genetically encodable MRI contrast agents, and other projects...

Contact Me
replace x with caltech

1200 E California Blvd
Pasadena, Los Angeles County 91106

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